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Drug Discovery Assay Kits: Comprehensive & Reliable Screening Solutions
Rapidly screen therapeutic candidates today and accelerate drug development decisions for a better tomorrow.
With INDIGO’s Drug Discovery Assay Kits, you can:
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CB1R Reporter Assay Kit
Species
Human
Target Type
GPCR
Associated Disease
Cancer, Cardiovascular, Dermatitis, Dyslipidemia, NASH/NAFLD, Neurodegenerative, Obesity, Osteoporosis
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Cyn Monkey FXR Reporter Assay Kit
Species
Cyn Monkey
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cardiovascular, Dermatitis, Dyslipidemia, Kidney Disease, NASH/NAFLD, Obesity, Reproduction
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Cyn Monkey PGR Reporter Assay Kit
Species
Cyn Monkey
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Autoimmune, Cancer, Cardiovascular, Dermatitis, Dyslipidemia, Obesity, Osteoporosis, Reproduction
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Cyn Monkey PPARa Reporter Assay Kit
Species
Cyn Monkey
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cancer, Cardiovascular, Dermatitis, Dyslipidemia, NASH/NAFLD, Obesity, Reproduction
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Cyn Monkey PPARd Reporter Assay Kit
Species
Cyn Monkey
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cancer, Dermatitis, Dyslipidemia, NASH/NAFLD, Neurodegenerative, Obesity, Reproduction, Wound Healing
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Cyn Monkey PPARg Reporter Assay Kit
Species
Cyn Monkey
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Autoimmune, Cancer, Cardiovascular, Dermatitis, Dyslipidemia, Kidney Disease, NASH/NAFLD, Obesity, Osteoporosis, Reproduction
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Cyn Monkey PPARg Reporter Assay Kit (Copy) Test
Species
This is an all-inclusive cell-based luciferase reporter assay kit targeting the Cynomolgus Monkey Peroxisome Proliferator-Activated Receptor Gamma. INDIGO’s cPPAR gamma reporter assay utilizes proprietary non-human mammalian cells that have been engineered to provide constitutive expression of the cPPAR gamma. In addition to cPPAR gamma Reporter Cells, this kit provides two optimized media for use during cell culture and in diluting the user’s test samples, a reference agonist, Luciferase Detection Reagent, and a cell culture-ready assay plate. The principal application of this assay is in the screening of test samples to quantify any functional activity, either agonist or antagonist, that they may exert against cPPAR gamma. This kit provides researchers with clear, reproducible results, exceptional cell viability post-thaw, and consistent results lot to lot. Kits must be stored at -80C. Do not store in liquid nitrogen. Note: reporter cells cannot be refrozen or maintained in extended culture.
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Cyn Monkey PXR Reporter Assay Kit
Species
Cyn Monkey
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cancer, Cardiovascular, Kidney Disease, NASH/NAFLD, Wound Healing
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Dog FXR Reporter Assay Kit
Species
Dog
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Cardiovascular, Dermatitis, Dyslipidemia, Kidney Disease, NASH/NAFLD, Obesity, Reproduction
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Dog LXRa Reporter Assay Kit
Species
Dog
Target Type
Nuclear Hormone Receptor
Nuclear Receptor Orthologs
Associated Disease
Autoimmune, Cancer, Cardiovascular, NASH/NAFLD, Reproduction
Evaluate Drug Candidates’ Safety from Every Angle with INDIGO’s Drug Discovery Assays
Did you know that almost 90% of candidate drugs fail in the first stage of trials?
Your drug lead can reverse the trend!
With INDIGO’s in vitro drug discovery assays, save resources and energy by identifying and characterizing adverse effects and potential risks before your drug candidate progresses further in the drug development process.
Explore INDIGO’s in vitro solutions in the broad categories of Prospective Screens, Safety Pharmacology, and Retrospective Screens, and start focusing your efforts on the best drug leads only.
Prospective Screens
Explore drug-drug interactions with INDIGO’s Nuclear Receptor Profiling and accurately predict the adverse effects of your molecule of interest.
Or dig deeper downstream of nuclear receptor activation through quantification of gene expression using INDIGO’s assay services.
Safety Pharmacology
Evaluate your compounds on major receptors with INDIGO’s reporter assay panels to understand their biological and toxicological effects better.
Identify therapeutic agents with the highest selectivity and lowest potential for off-target and unwanted effects with INDIGO’s cell-based receptor assays.
Retrospective Screens
Unexpected results from clinical trials or animal studies? Trouble-shoot with INDIGO's large portfolio of ortholog assays to quickly determine if the response observed in laboratory animals is concordant with humans.
Explore Additional INDIGO’s in vitro Solutions to Improve Drug Discovery
Quickly gain insights into the mechanisms underlying the involvement of key receptors in various diseases with INDIGO’s reporter assays.
Understand a compound's on- and off-target effects and liabilities on overlapping pathways with nuclear receptors functional classifications.
