Cardiovascular Disease
Cardiovascular Disease
INDIGO’s assay kits and services can provide valuable information for your cardiovascular disease research. Whether you are interested in a single-receptor assay or a full-panel study, we can help you obtain the data you need quickly.
Receptors for Cardiovascular Disease Research
Nuclear receptors and other receptors are critical regulators of metabolism, inflammation, and regeneration. Understanding the mechanisms underlying the involvement of nuclear receptors, as well as other receptors in the pathogenesis of cardiovascular disease and atherosclerosis may offer targets for the development of new treatments.
Indigo Assays for Cardiovascular Disease Research
- AhR
- ERα (NR3A1)
- ERβ (NR3A2)
- ERRγ (NR3B3)
- GHR
- LXRα (NR1H3)
- LXRβ (NR1H2)
- PPARα (NR1C1)
- RORα (NR1F1)
- TEAD/YAP (Hippo Pathway)
- TGFβR
- VEGFR2
Cardiovascular Disease
Cardiovascular disease or heart disease describes a range of conditions that affect the cardiovascular system including blood vessel diseases, arrhythmias, and cardiomyopathy. Causes including diabetes, smoking, stress, obesity, and an existing family history have been associated with cardiovascular disease. A major indicator of developing cardiovascular disease is atherosclerosis. Atherosclerosis happens when plaque builds up in and on the walls of the arteries. This buildup of plaque narrows the arteries, making it hard for blood to flow.
Signs and symptoms vary for different types of cardiovascular disease, but often include fatigue, high blood pressure, chest pain, and shortness of breath. Complications associated with cardiovascular disease can lead to aneurysms, cardiac arrest, heart failure, stroke, and death. In fact, cardiovascular diseases are regularly among the top global causes of death reported by the World Health Organization. Diagnosis of cardiovascular disease typically involves an electrocardiography, echocardiography, or stress testing to screen for the disease.
Initial treatment of cardiovascular disease largely focuses on diet, lifestyle changes, as well as medication. If these treatments are not enough, surgical intervention may be required.
EXPAND CONTENTRelated Products and Services
Drug Discovery Assay Kits
Get fast, clear, reproducible results from INDIGO’s all-inclusive reporter assay kits. No cell culture required!
Reporter Assay Services
Rapidly gain a clear overview of chemicals, pharmaceutical compounds, or environmental samples on key biological receptors.
Custom Assay Development
Contact our team of specialists and design custom assays tailored to your needs.
Related Information
[fl_builder_insert_layout id=”211094″ type=”fl-builder-template”] [fl_builder_insert_layout id=”211095″ type=”fl-builder-template”] [fl_builder_insert_layout id=”211096″ type=”fl-builder-template”]What Our Customers Say
“The fact that they do have this comprehensive panel…essentially you can pick and choose which of the members of the panel you want to run.”
Linda Scientist“The overall experience went smoothly, and I got valuable data that helped me advance several molecules through the discovery pipeline.”
Olivia Associate Director“These assays don’t require any optimization as far as growth conditions of the cells…you thaw the cells, treat them, and get an IC50 or an activity readout the next day, which is very convenient.”
Mark Principal Scientist